Nuclear receptor NR5A2 and bone: gene expression and association with bone mineral density

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Nuclear receptor NR5A2 and bone: gene expression and association with bone mineral density.

OBJECTIVE There is growing evidence for a link between energy and bone metabolism. The nuclear receptor subfamily 5 member A2 (NR5A2) is involved in lipid metabolism and modulates the expression of estrogen-related genes in some tissues. The objective of this study was to explore the influence of NR5A2 on bone cells and to determine whether its allelic variations are associated with bone minera...

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relationship between catsperb, nr5a2 gene polymorphisms and peak bone mineral density in college students in china.

peak bone mineral density (pbmd) is influenced by both genetic and environmental factors, genes explains most of variation. as the novel candidate genes catsperb and nr5a2 may have been associated with spinal pbmd in adult. this study was to investigate the relationship among these two genes^ pbmd and the life style factors in young female.the rs1298989 single nucleotide polymorphism (snp) of t...

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Relationship between CATSPERB, NR5A2 gene polymorphisms and Peak Bone Mineral Density in College Students in China

BACKGROUND Peak bone mineral density (PBMD) is influenced by both genetic and environmental factors, genes explains most of variation. As the novel candidate genes CATSPERB and NR5A2 may have been associated with spinal PBMD in adult. This study was to investigate the relationship among these two genes^ PBMD and the life style factors in young female. METHODS The rs1298989 single nucleotide p...

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ژورنال

عنوان ژورنال: European Journal of Endocrinology

سال: 2012

ISSN: 0804-4643,1479-683X

DOI: 10.1530/eje-11-0571